GeneTex
United States (US)

DLC1 antibody [N1], N-term

GTX106392_WB_19011506_303.jpg
GTX106392_39694_IHC_19011506_395.jpg

Cat No. GTX106392

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

171 kDa. ( Note )

Positive Control

H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Predict Reactivity

Mouse, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.84mg/ml

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DLC1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ARHGAP7 antibody, FLJ21120 antibody, HP antibody, STARD12 antibody, p122-RhoGAP antibody, DLC1 antibody, StAR-related lipid transfer (START) domain containing 12 antibody, rho-type GTPase-activating protein 7 antibody, deleted in liver cancer 1 variant 2 antibody, deleted in liver cancer 1 protein antibody, Rho-GTPase-activating protein 7 antibody, START domain-containing protein 12 antibody, rho GTPase-activating protein 7 antibody, deleted in liver cancer 1 antibody

Cellular Localization

Cytoplasm

Background

This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX106392_WB_19011506_303.jpg

GTX106392 WB Image

Sample(30 μg of whole cell lysate)
A:MOLT4(GTX27912)
7.5% SDS PAGE
GTX106392 diluted at 1:1500

GTX106392_39694_IHC_19011506_395.jpg

GTX106392 IHC-P Image

Immunohistochemical analysis of paraffin-embedded Pheochromocytoma xenograft, using DLC1(GTX106392) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf