GeneTex
United States (US)

DLC1 antibody

GTX54022_20180530_WB_18121410_251.jpg
GTX54022_20180530_IHC-P_18121410_380.jpg

Cat No. GTX54022

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

171 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dlc1 Rho Gtpase Activating Protein,Arhgap7,Hp,Stard12,P122-Rhogap,Dlc1

Background

This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]

Database

Research Area

DATA IMAGES
GTX54022_20180530_WB_18121410_251.jpg

GTX54022 WB Image

WB analysis of mouse lung tissue lysate using GTX54022 DLC1 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

GTX54022_20180530_IHC-P_18121410_380.jpg

GTX54022 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX54022 DLC1 antibody.
Dilution : 1:200