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DMC1 antibody

Cat. No. GTX11054

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Isotype

 IgG2a

Application

 WB, ICC/IF, IP

Reactivity

 Human, Mouse, Rat, Bovine
Package
100 μg ($399)
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APPLICATION

Application Note

For IF: Suggested starting dilution 1:100. Fix cells using a 4% paraformaldehyde solution and permeabilize using SDS (0.03% in a 4% paraformaldehyde solution). Incubate antibody overnight. For IP: Use at an assay dependent dilution. For WB: Suggested starting dilution 1:200. Predicted molecular weight: 41 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

38 kDa. ( Note )

Product Note

Specific for DMC1 - does not cross-react with the related protein Rad51.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.7 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein (Human).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA meiotic recombinase 1 , DMC1H , LIM15 , dJ199H16.1

Cellular Localization

Nucleus

Background

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Database

Research Area

REFERENCE

Application Reference

Chang HY et al. Nucleic Acids Res 2020; 48 (16) : 9135-9146 Microcephaly family protein MCPH1 stabilizes RAD51 filaments.
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations