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DMT1 antibody

Anti-DMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64686
Anti-DMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64686
Anti-DMT1 antibody used in Western Blot (WB). GTX64686
Anti-DMT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64686

Cat. No. GTX64686

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all DMT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC11A2 (NP_000608.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 11 member 2 , AHMIO1 , DCT1 , DMT1 , NRAMP2

Cellular Localization

Mitochondrion outer membrane,Cell membrane

Background

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

Database

Research Area

DATA IMAGES

Anti-DMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64686

GTX64686 IHC-P Image

IHC-P analysis of rat stomach tissue using GTX64686 DMT1 antibody.
Dilution : 1:100

Anti-DMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64686

GTX64686 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX64686 DMT1 antibody.
Dilution : 1:100

Anti-DMT1 antibody used in Western Blot (WB). GTX64686

GTX64686 WB Image

WB analysis of various sample lysates using GTX64686 DMT1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-DMT1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64686

GTX64686 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX64686 DMT1 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

Application Reference

LT Tsai et al. Antioxidants (Basel) 2023; 12 (11) : 1931 Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo
Application : WB
Seiwert N et al. Cell Death Dis 2020; 11 (9) : 787 Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399