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DNA ligase I antibody

Anti-DNA ligase I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55590
Anti-DNA ligase I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55590
Anti-DNA ligase I antibody used in Western Blot (WB). GTX55590

Cat. No. GTX55590

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all DNA ligase I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 565-790 of human LIG1 (NP_000225.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA ligase 1

Cellular Localization

Nucleus

Background

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-DNA ligase I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55590

GTX55590 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX55590 DNA ligase I antibody.
Blue : DAPI

Anti-DNA ligase I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55590

GTX55590 ICC/IF Image

ICC/IF analysis of A549 cells using GTX55590 DNA ligase I antibody.

Anti-DNA ligase I antibody used in Western Blot (WB). GTX55590

GTX55590 WB Image

WB analysis of various sample lysates using GTX55590 DNA ligase I antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399