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DNA ligase I antibody

Anti-DNA ligase I antibody used in Western Blot (WB). GTX70139

Cat. No. GTX70139

Host

Mouse

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
50 μl ($399)

APPLICATION

Application Note

Optima dilutions/concentrations should be determined by the researcher.

Calculated MW

102 kDa. ( Note )

Positive Control

HeLa

PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Full-length recombinant human DNA Ligase I protein

Purification

Unpurified
From polyclonal serum

Conjugation

Unconjugated

RRID

AB_372130

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA ligase 1

Cellular Localization

Nucleus

Background

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-DNA ligase I antibody used in Western Blot (WB). GTX70139

GTX70139 WB Image

Detection of human DNA Ligase I protein in Raji whole cell lysate using GeneTex polyclonal antiserum GTX70139.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399