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DNA polymerase delta antibody

Anti-DNA polymerase delta antibody used in Western Blot (WB). GTX70151

Cat. No. GTX70151

Reference 1

Host

 Mouse

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
50 μl ($399)
See all DNA polymerase delta products

APPLICATION

Application Note

For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

124 kDa. ( Note )

Positive Control

HeLa

PROPERTIES

Form

Liquid

Buffer

Unpurified Serum

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

Purification

Unpurified
From polyclonal serum.

Conjugation

Unconjugated

RRID

AB_370070

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA polymerase delta 1, catalytic subunit , CDC2 , CRCS10 , MDPL , POLD

Cellular Localization

Nucleus

Background

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-DNA polymerase delta antibody used in Western Blot (WB). GTX70151

GTX70151 WB Image

Detection of human polymerase delta protein in Jurkat whole cell lysate using GeneTex DNA polymerase delta polyclonal antiserum GTX70151.

REFERENCE

Application Reference

Matsumoto Y et al. J Mol Biol 2020; 432 (24) : 166698 Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation.
Application : WB
Reactivity : Human
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Package List Price ($)
$ 399