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DOCK8 antibody

Anti-DOCK8 antibody used in IHC (Paraffin sections) (IHC-P). GTX31578
Anti-DOCK8 antibody used in Western Blot (WB). GTX31578

Cat. No. GTX31578

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all DOCK8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

239 kDa. ( Note )

Positive Control

EL4 Cell Lysate(GTX27183) , Human Spleen Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8.The immunogen is located within the last 50 amino acids of DOCK8.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dedicator of cytokinesis 8 , HEL-205 , MRD2 , ZIR8

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-DOCK8 antibody used in IHC (Paraffin sections) (IHC-P). GTX31578

GTX31578 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31578 DOCK8 antibody.
Working concentration : 5 μg/ml

Anti-DOCK8 antibody used in Western Blot (WB). GTX31578

GTX31578 WB Image

WB analysis of EL4 cell lysate using GTX31578 DOCK8 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399