GeneTex

  • Country / Location Selection

United States (US)

DPM1 antibody, N-term

Anti-DPM1 antibody, N-term used in Western Blot (WB). GTX88562
Anti-DPM1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX88562

Cat. No. GTX88562

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all DPM1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.3μg/ml
IHC-P 3.75μg/ml
Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88562-PEP).

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence RELEVRSPRQNKYS-C, from the N Terminus of the protein sequence according to NP_003850.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dolichyl-phosphate mannosyltransferase subunit 1, catalytic , CDGIE , MPDS

Cellular Localization

Endoplasmic reticulum

Background

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-DPM1 antibody, N-term used in Western Blot (WB). GTX88562

GTX88562 WB Image

WB analysis of human liver lysate using GTX88562 DPM1 antibody, N-term.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

Anti-DPM1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX88562

GTX88562 IHC-P Image

IHC-P analysis of human tonsil using GTX88562 DPM1 antibody, N-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75μg/ml

REFERENCE

There are currently no references for DPM1 antibody, N-term (GTX88562). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for DPM1 antibody, N-term (GTX88562). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399