*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
U87-MG , SK-N-SH , SK-N-AS
Mouse, Rat, Bovine, Pig, Xenopus laevis(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.95mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CDGIE antibody, MPDS antibody, DPM1 antibody, DPM synthase antibody, dolichol monophosphate mannose synthase antibody, MPD synthase antibody, dolichyl-phosphate beta-D-mannosyltransferase antibody, dolichol-phosphate mannosyltransferase antibody, dolichol-phosphate mannose synthase antibody, mannose-P-dolichol synthase antibody, "dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit antibody"
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq]
GTX106196 WB Image
Various whole cell extracts (30 µg) were separated by 12% SDS-PAGE, and the membrane was blotted with DPM1 antibody [N1C2] (GTX106196) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.