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DR4 antibody [32A1380]

Anti-DR4 antibody [32A1380] used in Western Blot (WB). GTX11931
Anti-DR4 antibody [32A1380] used in Western Blot (WB). GTX11931

Cat. No. GTX11931

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 32A1380

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, MS

Reactivity

 Human
Package
50 μg ($399)
See all DR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 - 4 μg/ml
ICC/IF Assay dependent
FACS 1:20 - 1:2000
MS Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 10a , APO2 , CD261 , DR4 , TRAILR-1 , TRAILR1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq]

Database

  • Gene ID: 8797 TNFRSF10A
  • UniProt: O00220 TNFRSF10A

Research Area

DATA IMAGES

Anti-DR4 antibody [32A1380] used in Western Blot (WB). GTX11931

GTX11931 WB Image

WB analysis of Daudi cell lysate using GTX11931 DR4 antibody [32A1380].

Anti-DR4 antibody [32A1380] used in Western Blot (WB). GTX11931

GTX11931 WB Image

WB analysis of Daudi cell lysate using GTX11931 DR4 antibody [32A1380].
Dilution : 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399