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DR4 antibody [DR-4-02] (Low Endotoxin)

Cat No. GTX00590-00

Host

Mouse

Clonality

Monoclonal

Clone Name

DR-4-02

Isotype

IgG1

Application

ICC/IF, FACS, IP, Functional Assay

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
Functional Assay Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2 μm filter sterilized.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.

Purification

Protein A purified

Endotoxin

Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

APO2 , CD261 , DR4 , TNF receptor superfamily member 10a , TNFRSF10A , TRAILR1 , TRAIL-R1

Cellular Localization

Membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8797 TNFRSF10A
  • UniProt: O00220 TNFRSF10A

Research Area

REFERENCE

There are currently no references for DR4 antibody [DR-4-02] (Low Endotoxin) (GTX00590-00). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for DR4 antibody [DR-4-02] (Low Endotoxin) (GTX00590-00). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329