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DR4 antibody [DR-4-02]

Anti-DR4 antibody [DR-4-02] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00590

Cat No. GTX00590

Host

Mouse

Clonality

Monoclonal

Clone Name

DR-4-02

Isotype

IgG1

Application

ICC/IF, FACS, IP

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

APO2 , CD261 , DR4 , TNF receptor superfamily member 10a , TNFRSF10A , TRAILR1 , TRAIL-R1

Cellular Localization

Membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8797 TNFRSF10A
  • UniProt: O00220 TNFRSF10A

Research Area

DATA IMAGES

Anti-DR4 antibody [DR-4-02] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX00590

GTX00590 ICC/IF Image

ICC/IF analysis of HeLa transfected with TRAIL-R1 using GTX00590 DR4 antibody [DR-4-02].

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329