GeneTex

  • Country / Location Selection

United States (US)

DR4 peptide

Cat. No. GTX28446

Application

 Neutralizing/Inhibition

Species

 Human
Package
50 μg ($139)
See all DR4 products

APPLICATION

Application Note

The peptide is used for blocking the activity of DR4 (CT) (GTX28414). Incubatingthe peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks theantibody activity in Western blotting.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store the peptide at -20ºC, stable for one year.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Tnf Receptor Superfamily Member 10A , Apo2 , Cd261 , Dr4 , Trailr-1 , Trailr1 , Tnfrsf10A

Background

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor 1(TRAIL R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF kB activation in many tissues and cells.

Research Area

REFERENCE

There are currently no references for DR4 peptide (GTX28446). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for DR4 peptide (GTX28446). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 139