GeneTex

  • Country / Location Selection

United States (US)

DR5 antibody [7F4-F8-G11]

Anti-DR5 antibody [7F4-F8-G11] used in Western Blot (WB). GTX49151
Anti-DR5 antibody [7F4-F8-G11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49151

Cat. No. GTX49151

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7F4-F8-G11

Isotype

 IgG1

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all DR5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human TNFRSF10B protein fragments expressed in E.coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 10b , CD262 , DR5 , KILLER , KILLER/DR5 , TRAIL-R2 , TRAILR2 , TRICK2 , TRICK2A , TRICK2B , TRICKB , ZTNFR9

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Database

  • Gene ID: 8795 TNFRSF10B
  • UniProt: O14763 TNFRSF10B

Research Area

DATA IMAGES

Anti-DR5 antibody [7F4-F8-G11] used in Western Blot (WB). GTX49151

GTX49151 WB Image

WB analysis of mouse kindey, mouse brain, HCT116 and HeLa lysates using DR5 antibody.

Anti-DR5 antibody [7F4-F8-G11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49151

GTX49151 ICC/IF Image

ICC/IF analysis of HeLa cells using DR5 antibody at a dilution of 1:100.

REFERENCE

There are currently no references for DR5 antibody [7F4-F8-G11] (GTX49151). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for DR5 antibody [7F4-F8-G11] (GTX49151). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399