GeneTex
United States (US)

DRP1 antibody

GTX31901_392_ICC-IF_20180221_18121410_131.jpg
GTX31901_391_ICC-IF_20180221_18121410_795.jpg
GTX31901_3047_WB_20180221_18121410_902.jpg

Cat No. GTX31901

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse, Bovine
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

Positive Control

HeLa Cell Slide(GTX25529) , HeLa Cell Lysate

Specificity/Sensitivity

At least four isoforms of DNM1L are known to exist; this antibody will detect the two longest isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DRP1 antibody was raised against a 19 amino acid peptide near the center of human DRP1.The immunogen is located within amino acids 530 - 580 of DRP1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dynamin 1 Like,Dlp1,Drp1,Dvlp,Dymple,Empf,Empf1,Hdyniv,Opa5,Dnm1L

Background

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31901_392_ICC-IF_20180221_18121410_131.jpg

GTX31901 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31901 DRP1 antibody.
Working concentration : 20 μg/ml

GTX31901_391_ICC-IF_20180221_18121410_795.jpg

GTX31901 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31901 DRP1 antibody.
Working concentration : 5 μg/ml

GTX31901_3047_WB_20180221_18121410_902.jpg

GTX31901 WB Image

WB analysis of HeLa cell lysate using GTX31901 DRP1 antibody.
Working concentration : 1 μg/ml

REFERENCE
Package List Price ($)
$ 339