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DRP1 antibody

Anti-DRP1 antibody used in Western Blot (WB). GTX31901
Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31901
Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31901

Cat. No. GTX31901

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Bovine
Package
100 μg ($399)
See all DRP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

Positive Control

HeLa Cell Slide(GTX25529) , HeLa Cell Lysate

Product Note

At least four isoforms of DNM1L are known to exist; this antibody will detect the two longest isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DRP1 antibody was raised against a 19 amino acid peptide near the center of human DRP1.The immunogen is located within amino acids 530 - 580 of DRP1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887633

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynamin 1 like , DLP1 , DRP1 , DVLP , DYMPLE , EMPF , EMPF1 , HDYNIV , OPA5

Cellular Localization

Cytoplasm, cytosol,Golgi apparatus,Mitochondrion outer membrane

Background

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DRP1 antibody used in Western Blot (WB). GTX31901

GTX31901 WB Image

WB analysis of HeLa cell lysate using GTX31901 DRP1 antibody.
Working concentration : 1 μg/ml

Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31901

GTX31901 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31901 DRP1 antibody.
Working concentration : 5 μg/ml

Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31901

GTX31901 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31901 DRP1 antibody.
Working concentration : 20 μg/ml

REFERENCE

Application Reference

Chowdhury SR et al. J Cell Biol 2017; 216 (4) : 1071-1089 Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission.
Application : WB
Reactivity : Human
Tseng AH et al. Free Radic Biol Med 2013; 63 : 222-34 SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage.
Application : WB
Reactivity : Human, Bovine
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399