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DRP1 antibody

Anti-DRP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54040
Anti-DRP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54040
Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54040
Anti-DRP1 antibody used in Western Blot (WB). GTX54040

Cat. No. GTX54040

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all DRP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

82 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 411-710 of human DNM1L (NP_036193.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynamin 1 like , DLP1 , DRP1 , DVLP , DYMPLE , EMPF , EMPF1 , HDYNIV , OPA5

Cellular Localization

Cytoplasm, cytosol,Golgi apparatus,Mitochondrion outer membrane

Background

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Database

Research Area

DATA IMAGES

Anti-DRP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54040

GTX54040 IHC-P Image

IHC-P analysis of rat brain tissue using GTX54040 DRP1 antibody.
Dilution : 1:250

Anti-DRP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54040

GTX54040 IHC-P Image

IHC-P analysis of rat heart tissue using GTX54040 DRP1 antibody. Dilution : 1:250

Anti-DRP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54040

GTX54040 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX54040 DRP1 antibody.
Blue : DAPI

Anti-DRP1 antibody used in Western Blot (WB). GTX54040

GTX54040 WB Image

WB analysis of various sample lysates using GTX54040 DRP1 antibody.
Dilution : 1:8000
Loading : 25μg per lane

REFERENCE

Application Reference

Lam HYP et al. Parasitol Int 2021; 80 : 102231 Mitochondrial dynamics in Angiostrongylus cantonensis-infected mouse brain.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399