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DUS2L antibody

Anti-DUS2L antibody used in Western Blot (WB). GTX87067
Anti-DUS2L antibody used in IHC (Paraffin sections) (IHC-P). GTX87067

Cat. No. GTX87067

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all DUS2L products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human DUS2L (421-470).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

DUS2 , DUS2L , SMM1 , URLC8 , dihydrouridine synthase 2

Cellular Localization

Cytoplasm,Endoplasmic reticulum

Background

This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

Database

DATA IMAGES

Anti-DUS2L antibody used in Western Blot (WB). GTX87067

GTX87067 WB Image

WB analysis of RAW264.7 cell lysates using GTX87067 DUS2L antibody. The lane on the right is blocked with the synthesized peptide.

Anti-DUS2L antibody used in IHC (Paraffin sections) (IHC-P). GTX87067

GTX87067 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX87067 DUS2L antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399