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DUSP2 antibody

Orthogonal
Anti-DUSP2 antibody used in Western Blot (WB). GTX79395
Anti-DUSP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX79395

Cat. No. GTX79395

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all DUSP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:1,000
IHC-P 1:500
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide, KLH conjugated, corresponding to the residues L(506) S K S S S Q I R M S G L P A D N L A T(525) of human PAC1.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11166355

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dual specificity phosphatase 2 , PAC-1 , PAC1

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DUSP2 antibody used in Western Blot (WB). GTX79395

GTX79395 WB Image

Orthogonal

WB analysis of nuclear enriched extracts (30 μg lysate) of HEK-293 (Lane 1), HEK treated with TNF alpha (Serum starved for overnight followed by TNF alpha treatment for 30 minutes) (Lane 2) and 3T3-L1 (Lane 3) using GTX79395 DUSP2 antibody.
Dilution : 1:1000

Anti-DUSP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX79395

GTX79395 IHC-P Image

IHC-P analysis of human myenteric ganglia cells of the small intestine tissue using GTX79395 DUSP2 antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399