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DUSP8 antibody [N1], N-term

Anti-DUSP8 antibody [N1], N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100247
Anti-DUSP8 antibody [N1], N-term used in Western Blot (WB). GTX100247

Cat No. GTX100247

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
Package
100 μl ($319),
25 μl ($169)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Positive Control

Raji

Predict Reactivity

Mouse, Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.72 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DUSP8. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

dual specificity phosphatase 8 , C11orf81 , HB5 , HVH-5 , HVH8

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq]

Database

DATA IMAGES
Anti-DUSP8 antibody [N1], N-term used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100247

GTX100247 ICC/IF Image

Immunofluorescence analysis of paraformaldehyde-fixed A431, using DUSP8(GTX100247) antibody at 1:200 dilution.

Anti-DUSP8 antibody [N1], N-term used in Western Blot (WB). GTX100247

GTX100247 WB Image

Sample(30 μg of whole cell lysate)
A:Raji (GTX27908)
7.5% SDS PAGE
GTX100247 diluted at 1:1000

REFERENCE
There are currently no references for DUSP8 antibody [N1], N-term (GTX100247). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for DUSP8 antibody [N1], N-term (GTX100247). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169