*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Jurkat , Raji
Mouse, Rat(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.94 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human DUSP8. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Dual Specificity Phosphatase 8,C11Orf81,Hb5,Hvh-5,Hvh8,Dusp8
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq]
GTX115561 ICC/IF Image
DUSP8 antibody detects DUSP8 protein at cytoplasm by immunofluorescent analysis.
Sample: RD cells were fixed in ice-cold MeOH for 5 min.
Green: DUSP8 protein stained by DUSP8 antibody (GTX115561) diluted at 1:500.
Blue: Hoechst 33342 staining.
GTX115561 WB Image
DUSP8 antibody detects DUSP8 protein by western blot analysis.
A. 30 µg Jurkat whole cell extract
B. 30 µg Raji whole cell extract
DUSP8 antibody (GTX115561) dilution: 1:3000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.