GeneTex

  • Country / Location Selection

United States (US)

DUSP8 blocking peptide

Cat. No. GTX89940-PEP

Species

 Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX89940.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

AGDRLPRKVMDAK-C

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Dual Specificity Phosphatase 8 , C11Orf81 , Hb5 , Hvh-5 , Hvh8 , Dusp8

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for DUSP8 blocking peptide (GTX89940-PEP). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for DUSP8 blocking peptide (GTX89940-PEP). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 239