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DYNC1LI1 antibody [1B9]

Overexpression
Anti-DYNC1LI1 antibody [1B9] used in Western Blot (WB). GTX84596
Anti-DYNC1LI1 antibody [1B9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84596
Anti-DYNC1LI1 antibody [1B9] used in Flow cytometry (FACS). GTX84596
Anti-DYNC1LI1 antibody [1B9] used in Western Blot (WB). GTX84596

Cat. No. GTX84596

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1B9

Isotype

 IgG2b

Application

 WB, ICC/IF, FACS

Reactivity

 Human, Mouse, Dog, Monkey
Package
100 μl ($519)
See all DYNC1LI1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:2000
ICC/IF 1:100
FACS 1:100
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.93 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynein cytoplasmic 1 light intermediate chain 1 , DLC-A , DNCLI1 , LIC1

Cellular Localization

Cytoplasm

Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Database

Research Area

DATA IMAGES

Anti-DYNC1LI1 antibody [1B9] used in Western Blot (WB). GTX84596

GTX84596 WB Image

WB analysis of various cell lines using GTX84596 DYNC1LI1 antibody [1B9].
Loading : 10 ug per lane
Dilution : 1:200

Anti-DYNC1LI1 antibody [1B9] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX84596

GTX84596 ICC/IF Image

ICC/IF analysis of COS7 cells transiently transfected with DYNC1LI1 plasmid using GTX84596 DYNC1LI1 antibody [1B9].

Anti-DYNC1LI1 antibody [1B9] used in Flow cytometry (FACS). GTX84596

GTX84596 FACS Image

FACS analysis of HEK293T cells transfected with either DYNC1LI1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84596 DYNC1LI1 antibody [1B9].

Anti-DYNC1LI1 antibody [1B9] used in Western Blot (WB). GTX84596

GTX84596 WB Image

Overexpression

WB analysis of HEK293T cells transfected with DYNC1LI1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX84596 DYNC1LI1 antibody [1B9].
Loading : 5 ug per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519