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DYNC1LI1 antibody

Anti-DYNC1LI1 antibody used in Western Blot (WB). GTX120806
Anti-DYNC1LI1 antibody used in Western Blot (WB). GTX120806
Anti-DYNC1LI1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX120806

Cat. No. GTX120806

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all DYNC1LI1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:10000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

Positive Control

293T , HepG2 , mouse brain

Predict Reactivity

Rat, Bovine, Chicken, Xenopus tropicalis, Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human DYNC1LI1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2885532

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynein cytoplasmic 1 light intermediate chain 1 , DLC-A , DNCLI1 , LIC1

Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Database

Research Area

DATA IMAGES

Anti-DYNC1LI1 antibody used in Western Blot (WB). GTX120806

GTX120806 WB Image

DYNC1LI1 antibody detects DYNC1LI1 protein by Western blot analysis.
A. 30 μg 293T whole cell lysate/extract
B. 30 μg HepG2 whole cell lysate/extract
7.5 % SDS-PAGE
DYNC1LI1 antibody (GTX120806) dilution: 1:1000

Anti-DYNC1LI1 antibody used in Western Blot (WB). GTX120806

GTX120806 WB Image

DYNC1LI1 antibody detects DYNC1LI1 protein by western blot analysis.
A. 50 μg mouse brain lysate/extract
7.5 % SDS-PAGE
DYNC1LI1 antibody (GTX120806) dilution: 1:5000

Anti-DYNC1LI1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX120806

GTX120806 ICC/IF Image

DYNC1LI1 antibody detects DYNC1LI1 protein at cytoplasm by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde/PBS for 15 min.
Green: DYNC1LI1 protein stained by DYNC1LI1 antibody (GTX120806) diluted at 1:500.
Blue: Hoechst 33342 staining.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169