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DYNLL1 antibody [GT1324]

Recombinant antibody
Anti-DYNLL1 antibody [GT1324] used in Western Blot (WB). GTX03236
Anti-DYNLL1 antibody [GT1324] used in Western Blot (WB). GTX03236
Anti-DYNLL1 antibody [GT1324] used in IHC (Paraffin sections) (IHC-P). GTX03236

Cat. No. GTX03236

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1324

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($439)
See all DYNLL1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.77 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human DYNLL1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynein light chain LC8-type 1 , DLC1 , DLC8 , DNCL1 , DNCLC1 , LC8 , LC8a , PIN , hdlc1

Cellular Localization

Cytoplasm, cytoskeleton , Nucleus , Mitochondrion

Background

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DYNLL1 antibody [GT1324] used in Western Blot (WB). GTX03236

GTX03236 WB Image

Whole cell extract (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with DYNLL1 antibody [GT1324] (GTX03236) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-DYNLL1 antibody [GT1324] used in Western Blot (WB). GTX03236

GTX03236 WB Image

WB analysis of various samples using GTX03236 DYNLL1 antibody [GT1324].
Dilution : 1:1000
Loading : 25μg per lane

Anti-DYNLL1 antibody [GT1324] used in IHC (Paraffin sections) (IHC-P). GTX03236

GTX03236 IHC-P Image

IHC-P analysis of human colon tissue section using GTX03236 DYNLL1 antibody [GT1324].
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 439