GeneTex
United States (US)

DYRK2 antibody

GTX31833_364_ICC-IF_20180221_18121410_872.jpg
GTX31833_363_ICC-IF_20180221_18121410_391.jpg
GTX31833_2985_WB_20180221_18121410_790.jpg

Cat No. GTX31833

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

67 kDa. ( Note )

Positive Control

HEK293 Cell Slide(GTX25524) , HEK293 Cell Lysate(GTX27902)

Specificity/Sensitivity

Two isoforms of DYRK2 are known to exist; this antibody will recognize both isoforms. DYRK2 antibody will not cross-react with other DYRK family members.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DYRK2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DYRK2.The immunogen is located within amino acids 520 - 570 of DYRK2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2,Dyrk2

Background

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31833_364_ICC-IF_20180221_18121410_872.jpg

GTX31833 ICC/IF Image

ICC/IF analysis of 293 cells using GTX31833 DYRK2 antibody.
Working concentration : 20 μg/ml

GTX31833_363_ICC-IF_20180221_18121410_391.jpg

GTX31833 ICC/IF Image

ICC/IF analysis of 293 cells using GTX31833 DYRK2 antibody.
Working concentration : 10 μg/ml

GTX31833_2985_WB_20180221_18121410_790.jpg

GTX31833 WB Image

WB analysis of 293 cell lysate using GTX31833 DYRK2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329