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DcR1 antibody [4H10]

Cat No. GTX53033

Host

Mouse

Clonality

Monoclonal

Clone Name

4H10

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:20 - 1:100
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant TNFRSF10C EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD263 , DCR1 , DCR1TNFR , LIT , TNF receptor superfamily member 10c , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8794 TNFRSF10C
  • UniProt: O14798 TNFRSF10C

Research Area

REFERENCE

There are currently no references for DcR1 antibody [4H10] (GTX53033). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for DcR1 antibody [4H10] (GTX53033). Be the first to share your experience with this product.
SDS
PBS.pdf