APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The clone AT1E12 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TNFRSF12C protein.
Purification
Protein A Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
TNF receptor superfamily member 10c , CD263 , DCR1 , DCR1TNFR , LIT , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX57733 WB Image
WB analysis of Mouse liver tissue lysate using GTX57733 DcR1 antibody. Loading : 40 μg Dilution : 1:1000
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GTX57733 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX57733 DcR1 antibody. Blue: DAPI Green: Primary antibody Dilution: 1:100
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REFERENCE
There are currently no references for DcR1 antibody [AT1E12] (GTX57733). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for DcR1 antibody [AT1E12] (GTX57733). Be the first to share your experience with this product.