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DcR1 antibody

Anti-DcR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX22087
Anti-DcR1 antibody used in Western Blot (WB). GTX22087

Cat. No. GTX22087

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($449)
See all DcR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1μg/ml
ICC/IF Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to aa 111- 123 at the extracellular domain (ED) of human DcR1 precursor (accession no. AAB67104).

Purification

Purified by DEAE chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD263 , DCR1 , DCR1TNFR , LIT , TNF receptor superfamily member 10c , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8794 TNFRSF10C
  • UniProt: O14798 TNFRSF10C

Research Area

DATA IMAGES

Anti-DcR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX22087

GTX22087 ICC/IF Image

Immunofluorescent staining of DcR1 in rat liver tissue with DcR1 antibody (GTX22087) at 10μg/ml.

Anti-DcR1 antibody used in Western Blot (WB). GTX22087

GTX22087 WB Image

Western blot analysis of DcR1 in HeLa cell (A), mouse
(B) and rat (C) liver tissue lysates with DcR1 antibody
at 1μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 449