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DcR1 antibody

Cat. No. GTX70466

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all DcR1 products

APPLICATION

Application Note

Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Calculated MW

27 kDa. ( Note )

Product Note

Reacts with the N terminus of the mature human DcR1 protein.

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Purification

Serum

Conjugation

Unconjugated

RRID

AB_374155

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 10c , CD263 , DCR1 , DCR1-TNFR , LIT , TRAIL-R3 , TRAILR3 , TRID

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 8794 TNFRSF10C
  • UniProt: O14798 TNFRSF10C

Research Area

REFERENCE

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399