APPLICATION
Application Note
For IHC-P: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.
Calculated MW
Positive Control
Placenta
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.2% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide from the N-terminal extracellular domain of human DcR1 precursor protein
Purification
Protein A affinity purified
Conjugation
Unconjugated
RRID
AB_380208
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
TNF receptor superfamily member 10c , CD263 , DCR1 , DCR1-TNFR , LIT , TRAIL-R3 , TRAILR3 , TRID
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for DcR1 antibody (GTX73100). Be the first to share your publications with this product.
REVIEW
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