PRODUCT
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100-1:200 |
|
Note :
IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
This antibody has been validated by Autostainer including Agilent/Dako - Autostainer Link 48, Bond RX-Lecia, and Roche-Ventana Discovery ULTRA. The detailed steps by Autostainer please refer to the protocol.
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Not tested in other applications.
Calculated MW
Positive Control
Fallopian tube: A strong staining should be seen in the stroma while epithelial cells remain negative.
Negative Control
Fallopian tube: Epithelial cells should not show any staining.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA (Please contact us for PBS only format)
Preservative
0.05% sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human Decorin protein fragment (around aa212-336)
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
decorin , CSCD , DSPG2 , PG40 , PGII , PGS2 , SLRR1B
Cellular Localization
Secreted, extracellular space, extracellular matrix
Background
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
Database
Research Area
DATA IMAGES
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/templates/default/js/lightbox/images/loading.gif "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
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GTX04463 IHC-P Image
IHC-P analysis of human fallopian tube mucosa tissue using GTX04463 Decorin antibody [MSVA-537R] HistoMAX™.
Strong decorin immunostaining in the stroma while staining is completely lacking in epithelial cells decorin immunohistochemistry.
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GTX04463 IHC-P Image
IHC-P analysis of human urinary bladder tissue using GTX04463 Decorin antibody [MSVA-537R] HistoMAX™.
Strong decorin staining of the stroma while urothelium remains unstained in the urinary bladder.
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GTX04463 IHC-P Image
IHC-P analysis of human ovarian high-grade serous carcinoma (HGSC) tissue using GTX04463 Decorin antibody [MSVA-537R] HistoMAX™.
Serous high grade carcinoma of the ovary showing decorin staining of the stroma.
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REFERENCE
There are currently no references for Decorin antibody [MSVA-537R] HistoMAX™ (GTX04463). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Decorin antibody [MSVA-537R] HistoMAX™ (GTX04463). Be the first to share your experience with this product.
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/small/GTX04463/GTX04463_20230728_IHC-P_43_23072722_977.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/small/GTX04463/GTX04463_20230728_IHC-P_173_23072722_870.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/small/GTX04463/GTX04463_20230728_IHC-P_303_23072723_197.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/normal/GTX04463/GTX04463_20230728_IHC-P_43_23072722_977.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/normal/GTX04463/GTX04463_20230728_IHC-P_173_23072722_870.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")
![Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463](/upload/website/prouct_img/normal/GTX04463/GTX04463_20230728_IHC-P_303_23072723_197.webp "Anti-Decorin antibody [MSVA-537R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04463")