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Dectin-1 antibody [GE2] (Low endotoxin, azide free)

Anti-Dectin-1 antibody [GE2] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41459

Cat. No. GTX41459

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 GE2

Isotype

 IgG1

Application

 FACS, Functional Assay

Reactivity

 Human
Package
100 μg ($399)
See all Dectin-1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Neat-1/25
Functional Assay Assay dependent

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Product Note

This antibody recognizes both of these isoforms

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NIH3T3 cells expressing full length Dectin-1

Purification

Protein A purified
From tissue culture supernatant

Endotoxin

< 0.01 EU/μg (determined by the LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-type lectin domain containing 7A , BGR , CANDF4 , CD369 , CLECSF12 , DECTIN1 , SCARE2

Cellular Localization

Cell membrane

Background

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Dectin-1 antibody [GE2] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41459

GTX41459 FACS Image

FACS analysis of human peripheral blood monocytes using GTX41459 Dectin-1 antibody [GE2] (Low endotoxin, azide free).

REFERENCE

Clone Reference

Fu CW et al. J Med Chem 2021; 64 (1):527-542 Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis.
Submit a Reference

REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations