APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| Assay dependent |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Rat Spleen Tissue Lysate(GTX27945) , Human Spleen Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Dectin-1 antibody was raised against a 17 amino acid synthetic peptide near the center of human Dectin-1.The immunogen is located within amino acids 70 - 120 of Dectin-1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-type lectin domain containing 7A , BGR , CANDF4 , CD369 , CLECSF12 , DECTIN1 , SCARE2
Cellular Localization
Cell membrane
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31853 WB Image
WB analysis of rat spleen tissue lysate using GTX31853 Dectin-1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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GTX31853 ICC/IF Image
ICC/IF analysis of Jurkat cells using GTX31853 Dectin-1 antibody.
Dilution : 20 μg/ml
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GTX31853 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31853 Dectin-1 antibody.
Working concentration : 20 μg/ml
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GTX31853 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31853 Dectin-1 antibody.
Working concentration : 5 μg/ml
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REFERENCE
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REVIEW
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