APPLICATION
Application Note
FACS: 1:200 IF: 1:100 IHC: 1:200
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Serum
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human Dectin-2.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-type lectin domain containing 6A , CLEC4N , CLECSF10 , dectin-2
Cellular Localization
Membrane
Background
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Database
Research Area
DATA IMAGES
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GTX54664 IHC Image
IHC analysis of mouse thymus using Dectin-2 antibody.
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REFERENCE
There are currently no references for Dectin-2 antibody (GTX54664). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Dectin-2 antibody (GTX54664). Be the first to share your experience with this product.