GeneTex
United States (US)

Defensin alpha 1 antibody

Cat No. GTX30877

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

For ELISA: Use at a concentration of 2-4 μg/ml. For WB: Use at a concentration of 0.5-1 μg/ml. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

10 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.2 containing 50% glycerol, and 0.02% thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E. coli expressed human NP-1

Purification

Affinity purified with antigen

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Defensin Alpha 1,Def1,Defa2,Hnp-1,Hp-1,Hp1,Mrs,Defa1

Background

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq]

Database

Research Area

Package List Price ($)
$ 339