GeneTex
United States (US)

Defensin alpha 1 antibody

GTX64827_20180530_ICCIF_18121411_251.jpg
GTX64827_20180530_IHC-P_18121411_433.jpg
GTX64827_20180530_WB_18121411_245.jpg

Cat No. GTX64827

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

10 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-94 of human DEFA1 (NP_004075.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HP1 Antibody , DEFA2 Antibody , MRS Antibody , DEF1 Antibody , HNP1 Antibody , DEFA1 Antibody

Background

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014]

Database

Research Area

DATA IMAGES
GTX64827_20180530_ICCIF_18121411_251.jpg

GTX64827 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX64827 Defensin alpha 1 antibody.
Blue : DAPI

GTX64827_20180530_IHC-P_18121411_433.jpg

GTX64827 IHC-P Image

IHC-P analysis of rat heart tissue using GTX64827 Defensin alpha 1 antibody.
Dilution : 1:100

GTX64827_20180530_WB_18121411_245.jpg

GTX64827 WB Image

WB analysis of various samples using GTX64827 Defensin alpha 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319