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Dengue virus NS3 protein antibody

Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252
Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252
Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot and Immunoprecipitation (WB IP). GTX124252
Anti-Dengue virus NS3 protein antibody used in IHC (Paraffin sections) (IHC-P). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

Cat. No. GTX124252

Reference 98
1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS, IP, ELISA, IHC

Reactivity

 Dengue virus 2
Package
100 μl ($399),
25 μl ($169)
See all Dengue virus NS3 protein products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:2000
IHC-P Assay dependent
FACS Assay dependent
IP Assay dependent
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

Positive Control

Dengue virus type 1 infected BHK-21 , Dengue virus type 2 infected BHK-21 , Dengue virus type 3 infected BHK-21 , Dengue virus type 4 infected BHK-21

Product Note

Based on internal testing results, this antibody may cross react with Dengue virus type 1/3/4.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Dengue virus 2

Immunogen

Recombinant protein encompassing a sequence within the center region of Dengue virus NS3 protein (Dengue virus 2 (strain 16681 PDK 53)). The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11171668

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Dengue Virus Non-structural protein 3 , Dengue Virus NS3 , DENV Non-structural protein 3 , DENV NS3

Research Area

DATA IMAGES

Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252

GTX124252 ICC/IF Image

NS3 (Dengue virus) antibody detects NS3 (Dengue virus) protein at cytoplasm by immunofluorescent analysis.
Samples: BHK-21 cells mock (left) and infected with Dengue virus 3 (right) were fixed in MeOH.
Green: NS3 (Dengue virus) protein stained by NS3 (Dengue virus) antibody (GTX124252) diluted at 1:2000.
Blue: Hoechst 33342 staining.
Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252

GTX124252 ICC/IF Image

NS3 (Dengue virus) antibody detects NS3 (Dengue virus) protein at cytoplasm by immunofluorescent analysis.
Samples: BHK-21 cells mock (left) and infected with Dengue virus 4 (right) were fixed in MeOH.
Green: NS3 (Dengue virus) protein stained by NS3 (Dengue virus) antibody (GTX124252) diluted at 1:2000.
Blue: Hoechst 33342 staining.
Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252

GTX124252 ICC/IF Image

NS3 (Dengue virus) antibody detects NS3 (Dengue virus) protein at cytoplasm by immunofluorescent analysis.
Samples: BHK-21 cells mock (left) and infected with Dengue virus 1 (right) were fixed in MeOH.
Green: NS3 (Dengue virus) protein stained by NS3 (Dengue virus) antibody (GTX124252) diluted at 1:2000.
Blue: Hoechst 33342 staining.
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

NS3 (Dengue virus) antibody detects NS3 (Dengue virus) protein by western blot analysis.
A. 30 μg BHK-21 whole cell extract
B. 30 μg whole cell extract of Dengue virus type 1 infected BHK-21 cells
C. 30 μg whole cell extract of Dengue virus type 2 infected BHK-21 cells
D. 30 μg whole cell extract of Dengue virus type 3 infected BHK-21 cells
E. 30 μg whole cell extract of Dengue virus type 4 infected BHK-21 cells
7.5% SDS-PAGE
NS3 (Dengue virus) antibody (GTX124252) dilution: 1:2000
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The results may vary from different DENV strains, viral infection status, and culture conditions.
Reference: Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6795-9, J Infect Dis. 2011 Jun 15;203(12):1775-83.

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

Non-infected (–) and infected (+) BHK-21 whole cell extracts (15 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Dengue virus NS3 protein antibody (GTX124252) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Dengue virus NS3 protein antibody (GTX124252) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Dengue virus NS3 protein antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX124252

GTX124252 ICC/IF Image

NS3 (Dengue virus) antibody detects NS3 (Dengue virus) protein at cytoplasm by immunofluorescent analysis.
Samples: BHK-21 cells mock (left) and infected with Dengue virus 2 (right) were fixed in MeOH.
Green: NS3 (Dengue virus) protein stained by NS3 (Dengue virus) antibody (GTX124252) diluted at 1:2000.
Blue: Hoechst 33342 staining.
Anti-Dengue virus NS3 protein antibody used in Western Blot and Immunoprecipitation (WB IP). GTX124252

GTX124252 WB IP Image

The data was published in the journal PLoS Pathog in 2015. PMID: 26717518

Anti-Dengue virus NS3 protein antibody used in IHC (Paraffin sections) (IHC-P). GTX124252

GTX124252 IHC-P Image

The data was published in the journal Sci Rep in 2018. PMID: 29559699

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal Front Cell Infect Microbiol in 2018. PMID: 30186771

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal Viruses in 2020. PMID: 32121148

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal PLoS Pathog in 2015. PMID: 26717518

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal PLoS Pathog in 2015. PMID: 26717518

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal PLoS Pathog in 2015. PMID: 26717518

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal Front Microbiol in 2019. PMID: 31824450

Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252

GTX124252 WB Image

The data was published in the journal Viruses in 2020. PMID: 32121148

REFERENCE

Application Reference

Yang ML et al. iScience 2024; 27 (1) : 108422 Prothymosin α accelerates dengue virus-induced thrombocytopenia.
N Yu et al. bioRxiv 2024; Brain transcriptomics reveals features of the host response after dengue virus typeⅠinfection induced central nervous system injury in AGB6 mice
Application : ICC/IF
SH Wang et al. Virulence 2023; 14 (1) : 2279355 Lambda-free light chain: A serum marker of dengue disease via NS3 protease-mediated antibody cleavage
Application : ELISA
Zhou S et al. Virus Res 2023; 338 : 199234 Conessine inhibits enveloped viruses replication through up-regulating cholesterol level.
Hao J et al. Autophagy 2023; 19 (4) : 1332-1347 NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
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REVIEW

Dengue virus NS3 protein antibody Cat. No. GTX124252

Rating
( Average 5 based on 1 users reviews)
Application
Western Blot(WB)
( Average 5 based on 1 users reviews)
Anti-Dengue virus NS3 protein antibody used in Western Blot (WB). GTX124252
Date : Anonymous submitted on 03-May-2021
Score :
Application Tested : WB
Sample : A549 cells
Amount used : 10 μg
Blocking : 5% skim milk in TBST, 27°C, 1Hr
Primary Antibody : 1:2000, 4°C, 12Hr
Secondary Antibody : GTX213110-01, 1:2000, 27°C, 2Hr
Lane Description : Non-infected (mock) and infected (infection) A549 whole cell extracts (10 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Dengue virus NS3 protein antibody (GTX124252) diluted at 1:2000.
Submit a Review
Application Reference
Yang ML et al. iScience 2024; 27 (1):108422 Prothymosin α accelerates dengue virus-induced thrombocytopenia.
N Yu et al. bioRxiv 2024; Brain transcriptomics reveals features of the host response after dengue virus typeⅠinfection induced central nervous system injury in AGB6 mice
Application : ICC/IF
SH Wang et al. Virulence 2023; 14 (1):2279355 Lambda-free light chain: A serum marker of dengue disease via NS3 protease-mediated antibody cleavage
Application : ELISA
Zhou S et al. Virus Res 2023; 338:199234 Conessine inhibits enveloped viruses replication through up-regulating cholesterol level.
Hao J et al. Autophagy 2023; 19 (4):1332-1347 NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hu M et al. Microbiol Spectr 2023; 11 (4):e0042323 Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon.
Pan P et al. Signal Transduct Target Ther 2023; 8 (1):194 SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication.
Wei KC et al. Microbiol Spectr 2023; 11 (1):e0358622 Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1.
Palacios-R?palo SN et al. iScience 2023; 26 (12):108294 An ivermectin?- atorvastatin combination impairs nuclear transport inhibiting dengue infection in?vitro and in?vivo.
Han Y et al. Cell Stem Cell 2022; 29 (10):1475-1490.e6 A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Application : ICC/IF
Hu M et al. Viruses 2022; 14 (9) Development and Characterization of a Genetically Stable Infectious Clone for a Genotype I Isolate of Dengue Virus Serotype 1.
Application : ICC/IF
Udawatte DJ et al. Front Cell Infect Microbiol 2022; 12:926036 Dengue virus downregulates TNFR1- and TLR3-stimulated NF-κB activation by targeting RIPK1.
Application : WB, IP
Yousefi M et al. PLoS Pathog 2022; 18 (8):e1010763 TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.
Application : WB
Shwetha Shivaprasad et al. PLoS Pathog 2022; 18 (4):e1010163 Loquacious modulates flaviviral RNA replication in mosquito cells.
Application : WB
Thippayawan Ratanakomol et al. BMC Res Notes 2022; 15 (1):154 Oroxylin A shows limited antiviral activity towards dengue virus.
Application : WB
Yen-Chen Chen et al. Pharmaceuticals (Basel) 2021; 14 (4) Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability.
Application : ICC/IF
Carlos Noe Farfan-Morales et al. Sci Rep 2021; 11 (1):8743
Application : WB
Pan Pan et al. PLoS Pathog 2021; 17 (7):e1008603 DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction.
Application : WB
Zhou L et al. Antiviral Res 2021; 196:105210 Identification of Ascomycin against Zika virus infection through screening of natural product library.
Application : WB
Jhan MK et al. Cells 2021; 10 (11) Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Application : WB
Rathore APS et al. Front Immunol 2021; 12:681950 Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice.
Application : ICC/IF, FACS
Aviner R et al. Nature 2021; Cotranslational prolyl hydroxylation is essential for flavivirus biogenesis.
Application : WB
Burke JM et al. Sci Adv 2021; 7 (23) RNase L limits host and viral protein synthesis via inhibition of mRNA export.
Application : ICC/IF
Palacios-R?palo SN et al. Arch Virol 2021; 166 (5):1439-1446 Nuclear localization of non-structural protein 3 (NS3) during dengue virus infection.
Application : WB, ICC/IF
Lin JJ et al. PLoS Pathog 2021; 17 (3):e1009480 Aggressive organ penetration and high vector transmissibility of epidemic dengue virus-2 Cosmopolitan genotype in a transmission mouse model.
Application : IHC-P
Tammineni ER et al. Virology 2021; 553:81-93 Dantrolene hinders dengue virus-induced upregulation and translocation of calmodulin to cardiac cell nuclei.
Application : WB
Chuang FK et al. Int J Mol Sci 2020; 21 (11):4050 Antiviral Activity of Compound L3 against Dengue and Zika Viruses In Vitro and In Vivo
Application : WB
Vinit Upasani et al. Front Immunol 2020; 11:594813 Direct Infection of B Cells by Dengue Virus Modulates B Cell Responses in a Cambodian Pediatric Cohort.
Application : FACS
Kongmanas K et al. PLoS Negl Trop Dis 2020; 14 (11):e0008835 Immortalized stem cell-derived hepatocyte-like cells: An alternative model for studying dengue pathogenesis and therapy.
Brown RJP et al. Sci Adv 2020; 6 (45) Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice.
Arias-Arias JL et al. J Biol Chem 2020; 295 (8):2212-2226 A fluorescence-activatable reporter of flavivirus NS2B-NS3 protease activity enables live imaging of infection in single cells and viral plaques.
Campos RK et al. Nucleic Acids Res 2020; 48 (17):9872-9885 Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins.
Aguilar-Brise?o JA et al. Nat Commun 2020; 11 (1):3177 TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis.
Liu B et al. Virol Sin 2020; PTEN Lipid Phosphatase Activity Enhances Dengue Virus Production through Akt/FoxO1/Maf1 Signaling.
Application : ICC/IF
Vial T et al. Proc Natl Acad Sci U S A 2020; 117 (44):27627-27636 Mosquito metabolomics reveal that dengue virus replication requires phospholipid reconfiguration via the remodeling cycle.
Pahmeier F et al. J Virol 2020; (Epub) A Versatile Reporter System to Monitor Virus Infected Cells and Its Application to Dengue Virus and SARS-CoV-2.
Application : WB, ICC/IF
Lee YR et al. Kaohsiung J Med Sci 2020; 36 (11):911-919 Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection.
Application : WB
Afroz S et al. Front Immunol 2020; 11:1831 Dengue Virus Induced COX-2 Signaling Is Regulated Through Nutrient Sensor GCN2.
Application : WB
De Jes?s-Gonz?lez LA et al. Viruses 2020; 12 (6) The Nuclear Pore Complex: A Target for NS3 Protease of Dengue and Zika Viruses.
Application : WB
Wei KC et al. Viruses 2020; 12 (3) Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells.
Application : WB
Mohamed B et al. Sci Rep 2020; 10 (1):4040 Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses.
Application : WB
Butler, M et al. Viruses 2020; 12 (6):E654 Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism During Dengue Virus Serotype 2 Infection.
Application : WB
Hitakarun A et al. Sci Rep 2020; 10 (1):1499 Evaluation of the antiviral activity of orlistat (tetrahydrolipstatin) against dengue virus, Japanese encephalitis virus, Zika virus and chikungunya virus.
Application : WB
Evans AS et al. J Virol 2020; 94 (9) BPIFB3 Regulates Endoplasmic Reticulum Morphology To Facilitate Flavivirus Replication.
Shrivastava G et al. Front Immunol 2020; 11:352 Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome.
Application : WB
Xing H et al. Virus Res 2020; 275:197793 Zika NS2B is a crucial factor recruiting NS3 to the ER and activating its protease activity.
Application : ICC/IF
Pan P et al. Front Microbiol 2019; 10:2637 Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.
P?rez-Olais JH et al. Virus Res 2019; 274:197777 The activity of Aurora kinase B is required for dengue virus release.
Application : WB
Xie X et al. Cell Host Microbe 2019; 26 (5):606-622.e8 Dengue NS2A Protein Orchestrates Virus Assembly.
Application : WB
Chuang FK et al. Antimicrob Agents Chemother 2019; (Epub) Anti-inflammatory compound shows therapeutic safety and efficacy against flavivirus infection.
Application : WB
Rothan HA et al. Antiviral Res 2019; 171:104590 Small molecule grp94 inhibitors block dengue and Zika virus replication.
Rafael K. Campos et al. bioRxiv 2019; (Epub) Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins.
Application : WB
Hammack C et al. J Virol 2019; Zika virus infection induces DNA damage response in human neural progenitors that enhances viral replication.
Application : WB
Ooi YS et al. Nat Microbiol 2019; An RNA-centric dissection of host complexes controlling flavivirus infection.
Application : WB
Nandan S. Gokhale et al. bioRxiv 2019; (Epub) Altered m6A modification of specific cellular transcripts affects Flaviviridae infection
Application : WB
Abernathy E et al. PLoS Biol 2019; 17 (1):e2006926 Differential and convergent utilization of autophagy components by positive-strand RNA viruses.
Application : WB
Wei KC et al. Front Cell Infect Microbiol 2018; 8:268 Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells.
Frakolaki E et al. Cells 2018; 7 (12) The Role of Tissue Oxygen Tension in Dengue Virus Replication.
Application : WB
Arias-Arias JL et al. Am J Trop Med Hyg 2018; 99 (6):1451-1457 Dengue Virus Infection of Primary Human Smooth Muscle Cells.
Application : ICC/IF
Ramirez L et al. Virus Res 2018; 258:39-49 Dengue virus enters and exits epithelial cells through both apical and basolateral surfaces and perturbs the apical junctional complex.
Application : ICC/IF
Kao JC et al. PLoS Negl Trop Dis 2018; 12 (8):e0006715 The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR.
Application : WB
Juan Fidel Osuna-Ramos et al. bioRxiv 2018; (Epub) Ezetimibe inhibits Dengue virus infection in Huh 7 cells by blocking the cholesterol transporter Niemann–Pick C1–like 1 receptor.
Application : WB, FACS
Margot Cervantes-Salazar et al. bioRxiv 2018; (Epub) The Nonstructural Proteins 3 And 5 From Flavivirus Modulate Nuclear-Cytoplasmic Transport And Innate Immune Response Targeting Nuclear Proteins.
Application : WB
Azia S Evans et al. bioRxiv 2018; 2018 (Epub) BPIFB3 facilitates flavivirus infection by controlling RETREG1-dependent reticulophagy.
Application : ICC/IF
Zhang J et al. Cell Host Microbe 2018; 23 (6):819-831.e5 Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production.
Application : WB
Lai YC et al. Antiviral Res 2018; 155:28-38 Minocycline suppresses dengue virus replication by down-regulation of macrophage migration inhibitory factor-induced autophagy.
Application : WB
Sarathy VV et al. Sci Rep 2018; 8 (1):4900 Characterization of a murine model of non-lethal, symptomatic dengue virus infection.
Application : IHC-P
McFadden MJ et al. Viruses 2018; 10 (2) A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time.
Application : WB
Reid DW et al. J Virol 2018; (Epub) Dengue virus selectively annexes endoplasmic reticulum-associated translation machinery as a strategy for co-opting host cell protein synthesis.
Application : WB
Barbier V et al. Virology 2017; 500:149-160 Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission.
Hishiki T et al. Front Microbiol 2017; 8:1674 Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle.
Reyes-Ruiz JM et al. Virology 2017; 515:74-80 Strand-like structures and the nonstructural proteins 5, 3 and 1 are present in the nucleus of mosquito cells infected with dengue virus.
Application : ICC/IF
Wu X et al. Cell 2017; (Epub) Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Application : WB
Wan SW et al. J Immunol 2017; (Epub) Therapeutic Effects of Monoclonal Antibody against Dengue Virus NS1 in a STAT1 Knockout Mouse Model of Dengue Infection.
Application : IHC-P
Lai YC et al. Sci Rep 2017; 7 (1):6975 Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection.
Application : IHC-P
Morales L et al. Biomedica 2017; 37:1 Polyclonal antibodies against recombinant dengue virus NS3 protein.
Application : WB, ICC/IF
Soto-Acosta R et al. PLoS Pathog 2017; 13 (4):e1006257 DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target.
Application : ICC/IF
Bautista-Carbajal P et al. Virology 2017; 501:188-198 The calmodulin antagonist W-7 (N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride) inhibits DENV infection in Huh-7 cells.
Application : WB
Campos RK et al. J Virol 2016; (Epub) RPLP1 and RPLP2 are essential flavivirus host factors that promote early viral protein accumulation.
Application : WB
Sun P et al. J Immunol Methods 2016; (Epub) NK cell degranulation as a marker for measuring antibody-dependent cytotoxicity in neutralizing and non-neutralizing human sera from dengue patients.
Application : FACS
Wu YW et al. Sci Rep 2016; 6:32243 Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization.
Application : ICC/IF
Cheng YL et al. Sci Rep 2016; 6:32000 Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes.
Application : WB
Tsai TT et al. Sci Rep 2016; 6:27670 Microglia retard dengue virus-induced acute viral encephalitis.
Application : IHC-P
Morales L et al. Biomedica 2016; 37:1 Anticuerpos policlonales contra recombinantes de la proteina NS3 del virus dengue: especificos y versatiles.
Marceau C.D. et al. Nature 2016; 535 (7610):159-63 Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens.
Application : WB
Medin CL et al. J Virol Methods 2015; 211:55-62 A plasmid-based reporter system for live cell imaging of dengue virus infected cells.
Application : ICC/IF
Zou J et al. J Virol 2015; 89 (7):3471-83 Mapping the Interactions between the NS4B and NS3 proteins of dengue virus.
Application : WB
Zou J et al. J Virol 2015; 89 (7):3455-70 Characterization of dengue virus NS4A and NS4B protein interaction.
Application : WB, ICC/IF
Yu CY et al. PLoS Pathog 2015; 11 (12):e1005350 Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins.
Chu YT et al. Immunology 2015; 146 (1):163-72 Mast cell-macrophage dynamics in modulation of dengue virus infection in skin.
Application : IHC
Naik NG et al. J Virol 2015; 89 (13):6746-60 Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication.
Application : WB
Angel-Ambrocio AH et al. Virus Res 2015; 198:19572 An embryonic heart cell line is susceptible to dengue virus infection.
Application : ICC/IF, FACS
Wan SW et al. PLoS One 2014; 9 (3):e92495 Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1.
Application : IHC
Sarathy VV et al. J Virol 2014; (Epub) a lethal murine infection model for dengue virus 3 in ag129 mice deficient in type i and ii * receptors leads to systemic disease.
Application : IHC-P
Soto-Acosta R et al. Antiviral Res 2014; 109C:132-140 Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus.
Application : WB
St John AL et al. Elife 2013; 2:e00481 Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.
Application : ICC/IF
Barratt-Boyes SM et al. Comp Immunol Microbiol Infect Dis 2012; 35 (3):217-8 Comparative immunology, microbiology and infectious diseases. Introduction.
Application : ICC/IF
Wu CW et al. Patent. 2012; Method and system for monitoring and recording viral infection process and screening for agents that inhibit virus infection
Application : ICC/IF
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