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Derlin 1 antibody, C-term

Anti-Derlin 1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81054
Anti-Derlin 1 antibody, C-term used in Flow cytometry (FACS). GTX81054
Anti-Derlin 1 antibody, C-term used in Western Blot (WB). GTX81054
Anti-Derlin 1 antibody, C-term used in Western Blot (WB). GTX81054

Cat. No. GTX81054

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all Derlin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human DERL1.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

derlin 1 , DER-1 , DER1 , derlin-1

Cellular Localization

Endoplasmic reticulum membrane

Background

The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

Database

Research Area

DATA IMAGES

Anti-Derlin 1 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX81054

GTX81054 IHC-P Image

IHC-P analysis of human brain tissue using GTX81054 Derlin 1 antibody, C-term.

Anti-Derlin 1 antibody, C-term used in Flow cytometry (FACS). GTX81054

GTX81054 FACS Image

FACS analysis of HeLa cells using GTX81054 Derlin 1 antibody, C-term.
Top histogram : negative control
Bottom histogram : HeLa cells

Anti-Derlin 1 antibody, C-term used in Western Blot (WB). GTX81054

GTX81054 WB Image

WB analysis of NIH-3T3 cell lysate (35ug/lane) using GTX81054 Derlin 1 antibody, C-term.

Anti-Derlin 1 antibody, C-term used in Western Blot (WB). GTX81054

GTX81054 WB Image

WB analysis of SK-BR-3 whole cell lysate using GTX81054 Derlin 1 antibody, C-term.
Loading : 20 μg per lane
Dilution : 1:16000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399