APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
1:100-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 0.5% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant Protein
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CSM1,CSM2,DES,LGMD2R,desmin,Desmin
Cellular Localization
Cytoplasm,Myofibril,Sarcomere,Z line,Cell membrane,Sarcolemma,Nucleus
Background
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX34350 IHC-P Image
IHC-P analysis of mouse lung tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98ºC, 20min) Dilution : 1:200
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GTX34350 WB Image
WB analysis of HeLa and HepG2 cell lysates using GTX34350 Desmin antibody [1B12].
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GTX34350 IHC-P Image
IHC-P analysis of mouse heart tissue using GTX34350 Desmin antibody [1B12]. Dilution : 1:200
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GTX34350 IHC-P Image
IHC-P analysis of mouse spleen tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98ºC, 20min) Dilution : 1:200
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GTX34350 IHC-P Image
IHC-P analysis of mouse skeletal muscle tissue using GTX34350 Desmin antibody [1B12]. Dilution : 1:200
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GTX34350 IHC-P Image
IHC-P analysis of human lung tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98ºC, 20min) Dilution : 1:200
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GTX34350 IHC-P Image
IHC-P analysis of rat heart tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98ºC, 20min) Dilution : 1:200
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GTX34350 IHC-P Image
IHC-P analysis of rat spleen tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98ºC, 20min) Dilution : 1:200
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REFERENCE
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REVIEW
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