GeneTex
United States (US)

Desmin antibody, C-term

GTX88510_941_IHC-P_18122102_825.jpg
GTX88510_942_IHC-P_18122102_423.jpg
GTX88510_2275_WB_18122102_364.jpg
GTX88510_940_IHC-P_18122102_299.jpg

Cat No. GTX88510

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat, Pig
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.3-1μg/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88510-PEP).

Predict Reactivity

Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-RDGEVVSEATQQQHE, from the C Terminus of the protein sequence according to NP_001918.3.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Desmin,Cdcd3,Cmd1F,Csm1,Csm2,Lgmd1D,Lgmd1E,Lgmd2R,Des

Cellular Localization

Cytoplasm

Background

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX88510_941_IHC-P_18122102_825.jpg

GTX88510 IHC-P Image

IHC-P analysis of human heart using GTX88510 Desmin antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5µg/ml

GTX88510_942_IHC-P_18122102_423.jpg

GTX88510 IHC-P Image

IHC-P analysis of human skeletal muscle using GTX88510 Desmin antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5µg/ml

GTX88510_2275_WB_18122102_364.jpg

GTX88510 WB Image

WB analysis of human (A), mouse (B), rat (C) and pig (D) skeletal muscle lysate using GTX88510 Desmin antibody, C-term.
Dilution : 1µg/ml
Loading : 35µg protein in RIPA buffer

GTX88510_940_IHC-P_18122102_299.jpg

GTX88510 IHC-P Image

IHC-P analysis of human heart using GTX88510 Desmin antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml

Package List Price ($)
$ 329