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Desmin antibody [RM234]

Anti-Desmin antibody [RM234] used in Western Blot (WB). GTX33613
Anti-Desmin antibody [RM234] used in IHC (Paraffin sections) (IHC-P). GTX33613

Cat No. GTX33613

Host

Rabbit

Clonality

Monoclonal

Clone Name

RM234

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($279)

APPLICATION

Application Note

Immunohistochemistry (IHC): 1:1000-1:4000 dilution, Western Blot (WB): 1:1000-1:2000 dilution.

Calculated MW

54 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology.

PROPERTIES

Form

Liquid

Buffer

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A peptide corresponding to human Desmin

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Desmin , Cdcd3 , Cmd1F , Csm1 , Csm2 , Lgmd1D , Lgmd1E , Lgmd2R , Des

Cellular Localization

Cytoplasm

Background

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Desmin antibody [RM234] used in Western Blot (WB). GTX33613

GTX33613 WB Image

Western Blot of mouse heart tissue lysates using Anti-Desmin RM234 at a 1:1000 dilution, showed a band of Desmin (~54 kDa) expressed in mouse heart.

Anti-Desmin antibody [RM234] used in IHC (Paraffin sections) (IHC-P). GTX33613

GTX33613 IHC-P Image

Immunohistochemical staining of formalin fixed and paraffin embedded human heart tissue sections using Anti-Desmin RM234 at a 1:4000 dilution.

REFERENCE

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REVIEW

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Package List Price ($)
$ 279