GeneTex
United States (US)

Desmoglein 1 antibody

GTX64482_20180530_IHC-P_18121411_646.jpg
GTX64482_20180530_WB_18121411_260.jpg

Cat No. GTX64482

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

114 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CDHF4 Antibody , DSG1 Antibody , DG1 Antibody , PPKS1 Antibody , DSG Antibody , SPPK1 Antibody

Background

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Database

DATA IMAGES
GTX64482_20180530_IHC-P_18121411_646.jpg

GTX64482 IHC-P Image

IHC-P analysis of human trachea tissue using GTX64482 Desmoglein 1 antibody.
Dilution : 1:100

GTX64482_20180530_WB_18121411_260.jpg

GTX64482 WB Image

WB analysis of various samples using GTX64482 Desmoglein 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319