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Desmoglein 1 antibody

Anti-Desmoglein 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64482
Anti-Desmoglein 1 antibody used in Western Blot (WB). GTX64482
Anti-Desmoglein 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64482

Cat. No. GTX64482

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all Desmoglein 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

114 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

desmoglein 1 , CDHF4 , DG1 , DSG , EPKHE , EPKHIA , PPKS1 , SPPK1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Database

Research Area

DATA IMAGES

Anti-Desmoglein 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64482

GTX64482 IHC-P Image

IHC-P analysis of rat skin tissue using GTX64482 Desmoglein 1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-Desmoglein 1 antibody used in Western Blot (WB). GTX64482

GTX64482 WB Image

WB analysis of various sample lysates using GTX64482 Desmoglein 1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Desmoglein 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64482

GTX64482 IHC-P Image

IHC-P analysis of human trachea tissue using GTX64482 Desmoglein 1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399