APPLICATION
Application Note
IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Positive Control
Colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
Product Note
GTX12078 reacts with Desmoglein 2. Does not cross-react with Desmoglein 1 or Desmoglein 3.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Unfortunately, this information is considered to be commercially sensitive
Purification
Protein G purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
desmoglein 2 , CDHF5 , HDGC
Cellular Localization
Cell membrane; Single-pass type I membrane protein
Background
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
Database
Research Area
REFERENCE
There are currently no references for Desmoglein 2 antibody [6D8] (GTX12078). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Desmoglein 2 antibody [6D8] (GTX12078). Be the first to share your experience with this product.