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Desmoglein 2 antibody [6D8]

Cat. No. GTX12078

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6D8

Isotype

 IgG1

Application

 WB, ICC/IF, IP

Reactivity

 Human
Package
50 μg ($399)
See all Desmoglein 2 products

APPLICATION

Application Note

IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

122 kDa. ( Note )

Positive Control

Colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Product Note

GTX12078 reacts with Desmoglein 2. Does not cross-react with Desmoglein 1 or Desmoglein 3.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Unfortunately, this information is considered to be commercially sensitive

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

desmoglein 2 , CDHF5 , HDGC

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399