IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user.
Colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
GTX12078 reacts with Desmoglein 2. Does not cross-react with Desmoglein 1 or Desmoglein 3.
PBS, 0.1% BSA
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Unfortunately, this information is considered to be commercially sensitive
Protein G purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
desmoglein 2 , CDHF5 , HDGC
Cell membrane; Single-pass type I membrane protein
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]