GeneTex
  • Country / Location Selection

United States (US)

Desmoglein 3 antibody [DSG3/1535]

Anti-Desmoglein 3 antibody [DSG3/1535] used in IHC (Paraffin sections) (IHC-P). GTX34677
Anti-Desmoglein 3 antibody [DSG3/1535] used in IHC (Paraffin sections) (IHC-P). GTX34677

Cat No. GTX34677

Host

Mouse

Clonality

Monoclonal

Clone Name

DSG3/1535

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

108 kDa. ( Note )

Specificity/Sensitivity

This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Recombinant human DSG3 extracellular protein fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CDHF6,DSG3,PVA,desmoglein 3,Desmoglein 3

Cellular Localization

Cell membrane,Cell junction,Desmosome

Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-Desmoglein 3 antibody [DSG3/1535] used in IHC (Paraffin sections) (IHC-P). GTX34677

GTX34677 IHC-P Image

IHC-P analysis of human lung squamous cell carcinoma tissue using GTX34677 Desmoglein 3 antibody [DSG3/1535].

Anti-Desmoglein 3 antibody [DSG3/1535] used in IHC (Paraffin sections) (IHC-P). GTX34677

GTX34677 IHC-P Image

IHC-P analysis of human skin tissue using GTX34677 Desmoglein 3 antibody [DSG3/1535].

REFERENCE

There are currently no references for Desmoglein 3 antibody [DSG3/1535] (GTX34677). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Desmoglein 3 antibody [DSG3/1535] (GTX34677). Be the first to share your experience with this product.
Package List Price ($)
$ 339