APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1-2μg/ml |
1-2μg/ml for 30 minutes at RT |
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
|
Not tested in other applications.
Calculated MW
Product Note
This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human DSG3 extracellular protein fragment
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CDHF6 , DSG3 , PVA , desmoglein 3 , Desmoglein 3
Cellular Localization
Cell membrane,Cell junction,Desmosome
Background
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
Database
Research Area
DATA IMAGES
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GTX34677 IHC-P Image
IHC-P analysis of human skin tissue using GTX34677 Desmoglein 3 antibody [DSG3/1535].
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GTX34677 IHC-P Image
IHC-P analysis of human lung squamous cell carcinoma tissue using GTX34677 Desmoglein 3 antibody [DSG3/1535].
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REFERENCE
There are currently no references for Desmoglein 3 antibody [DSG3/1535] (GTX34677). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Desmoglein 3 antibody [DSG3/1535] (GTX34677). Be the first to share your experience with this product.