Desmoplakin (aa 1672 -1684) antibody, Internal

Cat. No. GTX88029

Host	Goat
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Human
Package	100 μg ($399)

See all Desmoplakin products

Datasheet
Document

View product citations for antibody GTX88029 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
IHC-P	3-6μg/ml
Note : IHC-P Human Heart shows staining of the junctons between cardiomuscular fibres.

Not tested in other applications.

Calculated MW

332 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88029-PEP).

Product Note

This antibody is expected to recognize reported isoform I (NP_004406.2) only.

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-QESVKQAHLRNEH, from the internal region of the protein sequence according to NP_004406.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

desmoplakin , DCWHKTA , DP

Cellular Localization

Cytoplasm, cytoskeleton , Cell membrane

Background

This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Database

Gene ID: 1832 DSP
UniProt: P15924 DSP

Research Area

DATA IMAGES

GTX88029 IHC-P Image

IHC-P analysis of human heart using GTX88029 Desmoplakin (aa 1672 -1684) antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty