In DMSO (10 mM)
Store at -20ºC. Protect from light and moisture.
10 mM (Please refer to the vial label for the specific concentration.)
>99% pure, as determined by TLC
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
20 dione , 4 diene 3 , 21 trihydroxy 1 , 4 pregnadiene 3 , 9a Fluoro 16a methyl 11?17a , 20dione , 4diene3 , 21trihydroxy1 , 4pregnadiene3 , 9aFluoro16amethyl11?17a
An anti-inflammatory glucocorticoid. Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells (IC?? = 5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexamethasone is sufficient to induce apoptosis following a 6-hour incubation at 37ºC