*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse testis
Rat, Bovine, Dog, Pig(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human Diablo. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
DIABLO-S antibody, FLJ10537 antibody, FLJ25049 antibody, SMAC antibody, SMAC3 antibody, DIABLO antibody, second mitochondria-derived activator of caspase antibody, mitochondrial Smac protein antibody, 0610041G12Rik antibody, direct IAP-binding protein with low pI antibody, "diablo homolog, mitochondrial antibody", diablo homolog (Drosophila) antibody
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq]
GTX106746 IHC-P Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Diablo(GTX106746) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min
GTX106746 WB Image
Sample (30 ug of whole cell lysate)
A: A431 (GTX27909)
12% SDS PAGE
GTX106746 diluted at 1:1000
GTX106746 WB Image
Mouse tissue extract (50 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with Diablo antibody [N1C3] (GTX106746) diluted at 1:500.