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Diablo antibody

Anti-Diablo antibody used in IHC (Paraffin sections) (IHC-P). GTX64409
Anti-Diablo antibody used in Western Blot (WB). GTX64409
Anti-Diablo antibody used in IHC (Paraffin sections) (IHC-P). GTX64409

Cat. No. GTX64409

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Diablo products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human DIABLO (NP_063940.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

diablo IAP-binding mitochondrial protein , DFNA64 , SMAC

Cellular Localization

Mitochondrion

Background

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-Diablo antibody used in IHC (Paraffin sections) (IHC-P). GTX64409

GTX64409 IHC-P Image

IHC-P analysis of rat testis tissue using GTX64409 Diablo antibody.
Dilution : 1:100

Anti-Diablo antibody used in Western Blot (WB). GTX64409

GTX64409 WB Image

WB analysis of various sample lysates using GTX64409 Diablo antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Diablo antibody used in IHC (Paraffin sections) (IHC-P). GTX64409

GTX64409 IHC-P Image

IHC-P analysis of mouse testis tissue using GTX64409 Diablo antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399