GeneTex
United States (US)

Dishevelled 1 antibody

GTX37714_20190129_WB_19012901_323.jpg

Cat No. GTX37714

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-2000
Not tested in other applications.

Calculated MW

75 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 31-90 amino acids of human Dishevelled 1

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dishevelled Segment Polarity Protein 1,Drs2,Dvl,Dvl1L1,Dvl1P1,Dvl1

Cellular Localization

Cell membrane,Cytoplasm,Cytoplasmic vesicle,Cytosol

Background

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX37714_20190129_WB_19012901_323.jpg

GTX37714 WB Image

WB analysis of rat brain (Lane 1) and rat lung (Lane 2) tissue lysates using GTX37714 Dishevelled 1 antibody.

Package List Price ($)
$ 319